{"id":381,"date":"2025-11-09T18:30:35","date_gmt":"2025-11-09T18:30:35","guid":{"rendered":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/?p=381"},"modified":"2025-11-09T18:30:35","modified_gmt":"2025-11-09T18:30:35","slug":"neues-medikament-caplyta-zur-behandlung-von-schweren-depressionen-zugelassen","status":"publish","type":"post","link":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/neues-medikament-caplyta-zur-behandlung-von-schweren-depressionen-zugelassen\/","title":{"rendered":"Neues Medikament Caplyta zur Behandlung von schweren Depressionen zugelassen"},"content":{"rendered":"

Caplyta (Wirkstoff Lumateperone) hat eine neue Zulassung f\u00fcr die Behandlung von schweren Depressionen (MDD) erhalten. Dies ist eine gute Nachricht, da etwa 22 Millionen Erwachsene in den USA von dieser Krankheit betroffen sind. Das Medikament wird nun als zus\u00e4tzliche Therapie zu Antidepressiva<\/a> eingesetzt. Caplyta ist bereits zur Behandlung von Schizophrenie und bipolarer Depression zugelassen, was die neue Zulassung f\u00fcr MDD zur gr\u00f6\u00dften Indikation macht. Caplyta ist ein atypisches Antipsychotikum, das einmal t\u00e4glich eingenommen wird. Johnson & Johnson (J&J), das Unternehmen, das Caplyta jetzt vermarktet, erwartet, dass das Medikament langfristig einen Umsatz von 5 Milliarden US-Dollar pro Jahr erzielen wird. Analysten sch\u00e4tzen, dass der Umsatz bis 2031 auf 2,7 Milliarden US-Dollar steigen k\u00f6nnte. Caplyta hat bereits im Jahr 2024 einen Umsatz von 680 Millionen US-Dollar erzielt. Die Zulassung basiert auf zwei gro\u00dfen Studien, die gezeigt haben, dass Caplyta in Kombination mit Antidepressiva die Symptome von Depressionen besser lindert als ein Placebo. Wie Caplyta genau wirkt, ist noch nicht vollst\u00e4ndig gekl\u00e4rt, aber es beeinflusst bestimmte Botenstoffe im Gehirn, wie Dopamin und Serotonin<\/a>. F\u00fcr Menschen, die trotz Antidepressiva noch unter Depressionen leiden, k\u00f6nnte Caplyta eine hilfreiche Erg\u00e4nzung sein. J&J bietet bereits mit Spravato (Esketamin) ein weiteres Medikament zur Behandlung von Depressionen an, das als Nasenspray angewendet wird. Spravato hat im Jahr 2024 einen Umsatz von 1 Milliarde US-Dollar erzielt, und die Prognose f\u00fcr 2031 liegt bei 3,8 Milliarden US-Dollar.<\/p>\n","protected":false},"excerpt":{"rendered":"

Caplyta (Wirkstoff Lumateperone) hat eine neue Zulassung f\u00fcr die Behandlung von schweren Depressionen (MDD) erhalten. Dies ist eine gute Nachricht, […]<\/p>\n","protected":false},"author":1,"featured_media":382,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[448],"tags":[],"class_list":["post-381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nachrichten"],"_links":{"self":[{"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/posts\/381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/comments?post=381"}],"version-history":[{"count":1,"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/posts\/381\/revisions"}],"predecessor-version":[{"id":405,"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/posts\/381\/revisions\/405"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/media\/382"}],"wp:attachment":[{"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/media?parent=381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/categories?post=381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hausarzt-dr-kahl.de\/apotheke\/wp-json\/wp\/v2\/tags?post=381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}